GENEL
ENHANCE YOUR RESEARCH

We have a scientific expertise in a large panel of human primary cells to mimic the real physiological response: keratinocytes, fibroblasts, melanocytes, adipocytes, endothelial cells and co-cultures.

Adipocytes

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Fibroblasts

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Our capacities

  •     Highly technological platform including Biological Safety level 2 Lab (BSL2 lab)
      
  •     Expert knowledge: cellular and molecular biologists, bioinformatics experts, PhD in Biology
      
  •     Transparency and validation at each step of the process
      
  •     Work within your time frame  

Gene Expression Profiling – GenScreening

Gain competitive advantage with your best active ingredient and recover from high R&D investments thanks to repositioning

Genscreening is an innovative solution to reveal the true potentiel of your cosmetic ingredient. We have identified the key genes involved in skin biology processes such as:

  •     Melanogenesis
      
  •     Epithelization and wound-healing
      
  •     Aging  
  •     Hydration
      
  •     Inflammation
      
  •     Detoxification…  

Essential process to choose the best ingredient:

  •     1. Treatment using our most relevant cellular model combining your active ingredient – one to several concentrations
      
  •     2. Gene expression analysis by RT-QPCR with our pathway-specific array.
      
  •     3. Statistical analysis & Biological interpretation  

Discover our GenScreening package – GSBT (GenScreening Basic Test)
one active – one concentration – one cellular model on 96 genes and/or microRNAs
Contact us to have more details and price

Modulation Gene Expression – GenAction

Tell the true story of your active ingredient
Reveal the mechanism of action of your best active ingredient and develop your product range

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GenAction provides
innovative approaches to:

  •     validate your cosmetic claims
      
  •     identify modes of action of your best cosmetic compound on human primary cells
      
  •     predict the cytotoxicity of your active ingredient  
Essential steps to understand why your active ingredient is the best:

  •     1. Modulation of regulated proteins and microRNAs – by inhibition and/or over expression
      
  •     2. Evaluation of cellular effects by immunofluorescence
      
  •     3. Data analysis with dedicated bioinformatics tools & biological interpretation  

Discover our GenAction package – GABT (GenAction Basic Test)
Regulation of 10 proteins – 2 phenotypes
or customized package
Contact us to have more details and price

INNOVATIVE SOLUTIONS
TO HIGHLIGHT NEW COSMETIC ACTIVE INGREDIENTS