Expertise in a broad range
of cell-based assays
At Genel, we possess expertise in a broad range of cell-based assays to mimic disease-related phenotypes.
Our cellular biology know-how allows us to determine the most efficient, appropriate assay design. Our proven experience in high-content screening enables us to ensure statistically-assisted assay optimization.
Transforming your biological questions into phenotypic tests.
Large panel of readouts:
- Signal transduction pathways
- Subcellular components
- Protein localization
- Interferon response
- Cell proliferation
- DNA damage
- …customized assays/outputs
Understand muscles’ energy production using organelle observation
Estimate the level of keratin 18/19 protein to study keratinocyte differentiation
Evaluate EdU incorporation to observe cell proliferation
Visualize gamma-H2AX foci to assess DNA damage
Identify the location of the miR let7 using proprietary hybridization
Study the totipotency of hES cells using protein detection
Cell-based Screening optimization
We are able to estimate the number of replicates and the number of cells that must be analyzed to get a statistically reliable screen. Before each screen, we propose an optimized quote that reduces repetition—and cuts costs.
- Save time by capturing only the number of images actually needed
- Plan ahead for future phenotypic screening conditions
- Increase your chances of target discovery success
from primary cells and 3d cellular models