A skin biopsy is a medical procedure in which a small section of skin is removed.

Traditionally used to diagnose dermatological conditions such as infections, inflammatory diseases, and skin cancers, biopsies have also become valuable tools in dermocosmetic research. By analyzing the skin at a cellular and molecular level, biopsies provide insights into how cosmetic products interact with the skin’s structure and function.

Punch biopsies includes deeper layers of the skin and allow researchers and clinicians to study specific layers of the skin—epidermis, dermis, or subcutaneous tissue—with high precision.

What makes skin biopsies particularly interesting in dermocosmetics is their ability to reveal biological responses to topical treatments. Through histological and molecular analysis, scientists can observe changes in collagen production, pigmentation, hydration, and inflammatory markers. This helps assess both the safety and efficacy of cosmetic formulations. In essence, skin biopsies serve as a bridge between clinical dermatology and cosmetic innovation, offering a deeper understanding of how products influence skin health and appearance.