ExoGEN

Mimic in vivo topical application through an innovative cell-based in vitro test

The skin is a complex organ composed of a variety of cells – keratinocytes, melanocytes, fibroblasts, immune cells and adipocytes – organized in different layers. These cells communicate to maintain homeostasis or to respond to stress. Cream application on the outer skin layer stimulates keratinocytes that send specific messages mainly via exosomes to target cells in the inner layers of the skin

Standard in vitro cell-dependant methods do not mimic the actual communication pathway triggered by the active ingredient.