Demonstrate the ability of your cosmetic ingredient to boost cellular energy production by mitochondria
Mitochondria are organelles located in every single cell within the organism. They are key for bioenergetics and are the actual « powerhouse » of cells. To maintain skin homeostasis, mitochondria accomplish several dynamic processes such as providing ATP, the primary energy source of skin cells, and mitophagy. Mitophagy is the selective degradation of mitochondria by autophagy. It often occurs to defective mitochondria following damage or stress.
However, with age and external aggressions, they become less effective and result in excess formation of Reactive Oxygen Species (ROS). Hence, damaged mitochondria accumulating in cells impact the skin’s functions, and eventually, its appearance.
GENergy proposes compelling ways of analysing mitochondrial turnover and homeostasis benefits of active ingredients.
GENergy methods
- Following stress, excess ROS formation leads to an accumulation of damaged mitochondria. Cells are subject to ATP depletion and to impaired mitophagy.
- Visualize these mechanismsand validate the ability of your active ingredient to revitalize mitochondria and the cell.
- Enhance the scientific images with gene and miRNA modulations.
Optimized process that guarantees fast and strong results.
Application of scientific techniques that respond to current need for mitochondria analysis.
Adaptable to any type of cells and any dermocosmetic pathway.
